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3,28 The combined activation of GLP-1 and GIP receptors more effectively reduces glucose levels and stimulates weight loss compared to the placebo, semaglutide and dulaglutide, or insulin
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For example, the LEADER trial showed that liraglutide reduced MACEs risk by 13%, while the SUSTAIN-6 trial indicated a 26% reduction with semaglutide
Participants, investigators, and study staff involved in clinical conduct and outcome assessment were blinded to treatment allocation